Search on: CONJUGATIVE METABOLIC DETOXICATION 
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Descriptor English:   Metabolic Detoxication, Phase II 
Descriptor Spanish:   Fase II de la Desintoxicación Metabólica 
Descriptor Portuguese:   Desintoxicação Metabólica Fase II 
Synonyms English:   Metabolic Detoxication, Conjugative
Metabolic Detoxification, Phase II
Phase II Detoxification
Conjugative Metabolic Detoxication
Conjugative Metabolic Detoxications
Detoxication, Conjugative Metabolic
Detoxications, Conjugative Metabolic
Detoxification, Phase II
Detoxifications, Phase II
Metabolic Detoxications, Conjugative
Phase II Detoxifications  
Tree Number:   G03.171.450.750
G03.787.225.450.750
G07.690.725.225.450.750
Definition English:   The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products. 
See Related English:   Antioxidant Response Elements
Protein Processing, Post-Translational
 
History Note English:   2006 
Allowable Qualifiers English:  
EH ethnology GE genetics
IM immunology PH physiology
RE radiation effects  
Record Number:   51247 
Unique Identifier:   D050217 

Occurrence in VHL:
 

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